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    O'Neil, James

    TitleChemist Staff Scientist/Engr
    SchoolLawrence Berkeley National Lab
    DepartmentMolecular Biophys & Integ Bio
    Address1 Cyclotron Road
    Berkeley CA 94720
    Phone510/486-5276
    vCardDownload vCard

      Collapse Bibliographic 
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Levin MD, Chen TQ, Neubig ME, Hong CM, Theulier CA, Kobylianskii IJ, Janabi M, O'Neil J, Toste FD. A catalytic fluoride-rebound mechanism for C(sp3)-CF3 bond formation. Science. 2017 Jun 23; 356(6344):1272-1276. PMID: 28642435.
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      2. Lockhart SN, Schöll M, Baker SL, Ayakta N, Swinnerton KN, Bell RK, Mellinger TJ, Shah VD, O'Neil J, Janabi M, Jagust WJ. Amyloid and tau PET demonstrate region-specific associations in normal older people. Neuroimage. 2017 Feb 21; 150:191-199. PMID: 28232190.
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      3. Spina S, Schonhaut DR, Boeve BF, Seeley WW, Ossenkoppele R, O'Neil J, Lazaris A, Rosen HJ, Boxer AL, Perry DC, Miller BL, Dickson DW, Parisi JE, Jagust WJ, Murray ME, Rabinovici GD. Frontotemporal dementia with the V337M MAPT mutation: Tau-PET and pathology correlations. Neurology. 2017 Jan 27. PMID: 28130473.
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      4. Seo SW, Ayakta N, Grinberg LT, Villeneuve S, Lehmann M, Reed B, DeCarli C, Miller BL, Rosen HJ, Boxer AL, O'Neil J, Jin LW, Seeley WW, Jagust WJ, Rabinovici GD. Regional correlations between [11C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort. Neuroimage Clin. 2017; 13:130-137. PMID: 27981028.
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      5. Aanei IL, ElSohly AM, Farkas ME, Netirojjanakul C, Regan M, Taylor Murphy S, O'Neil J, Seo Y, Francis MB. Biodistribution of Antibody-MS2 Viral Capsid Conjugates in Breast Cancer Models. Mol Pharm. 2016 Nov 07; 13(11):3764-3772. PMID: 27611245.
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      6. Ossenkoppele R, Schonhaut DR, Schöll M, Lockhart SN, Ayakta N, Baker SL, O'Neil J, Janabi M, Lazaris A, Cantwell A, Vogel J, Santos M, Miller ZA, Bettcher BM, Vossel KA, Kramer JH, Gorno-Tempini ML, Miller BL, Jagust WJ, Rabinovici GD. Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease. Brain. 2016 May; 139(Pt 5):1551-67. PMID: 26962052.
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      7. Ossenkoppele R, Schonhaut DR, Baker SL, O'Neil J, Janabi M, Ghosh PM, Santos M, Miller ZA, Bettcher BM, Gorno-Tempini ML, Miller BL, Jagust WJ, Rabinovici GD. Tau, amyloid, and hypometabolism in a patient with posterior cortical atrophy. Ann Neurol. 2015 Feb; 77(2):338-42. PMID: 25448043.
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      8. Roberts AD, Geddes CG, Matlis N, Nakamura K, O'Neil J, Shaw BH, Steinke S, van Tilborg J, Leemans WP. Measured bremsstrahlung photonuclear production of (99)Mo ((99m)Tc) with 34MeV to 1.7GeV electrons. Appl Radiat Isot. 2015 Feb; 96:122-8. PMID: 25484305.
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      9. Elman JA, Madison CM, Baker SL, Vogel JW, Marks SM, Crowley S, O'Neil J, Jagust WJ. Effects of Beta-Amyloid on Resting State Functional Connectivity Within and Between Networks Reflect Known Patterns of Regional Vulnerability. Cereb Cortex. 2016 Feb; 26(2):695-707. PMID: 25405944.
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      10. Elman JA, Oh H, Madison CM, Baker SL, Vogel JW, Marks SM, Crowley S, O'Neil J, Jagust WJ. Neural compensation in older people with brain amyloid-ß deposition. Nat Neurosci. 2014 Oct; 17(10):1316-8. PMID: 25217827.
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      11. Slowey AJ, Vandehey NT, O'Neil J, Boutchko R, Moses WW, Nico PS. Chemical stability of (99m)Tc-DTPA under aerobic and microbially mediated Fe(III)-reducing conditions in porous media. Appl Radiat Isot. 2014 Dec; 94:175-81. PMID: 25213084.
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      12. Vandehey NT, O'Neil J. Capturing [(11)C]CO2 for use in aqueous applications. Appl Radiat Isot. 2014 Aug; 90:74-8. PMID: 24705008.
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      13. Sánchez-Juan P, Ghosh PM, Hagen J, Gesierich B, Henry M, Grinberg LT, O'Neil J, Janabi M, Huang EJ, Trojanowski JQ, Vinters HV, Gorno-Tempini M, Seeley WW, Boxer AL, Rosen HJ, Kramer JH, Miller BL, Jagust WJ, Rabinovici GD. Practical utility of amyloid and FDG-PET in an academic dementia center. Neurology. 2014 Jan 21; 82(3):230-8. PMID: 24353340.
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      14. Hernandez AM, Huber JS, Murphy ST, Janabi M, Zeng GL, Brennan KM, O'Neil J, Seo Y, Gullberg GT. Longitudinal Evaluation of Left Ventricular Substrate Metabolism, Perfusion, and Dysfunction in the Spontaneously Hypertensive Rat Model of Hypertrophy Using Small-Animal PET/CT Imaging. J Nucl Med. 2013 Nov; 54(11):1938-45. PMID: 24092939.
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      15. Lehmann M, Ghosh PM, Madison C, Karydas A, Coppola G, O'Neil J, Huang Y, Miller BL, Jagust WJ, Rabinovici GD. Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patients. J Neurol Neurosurg Psychiatry. 2014 Mar; 85(3):266-73. PMID: 23965289.
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      16. Farkas ME, Aanei IL, Behrens CR, Tong GJ, Murphy ST, O'Neil J, Francis MB. PET Imaging and biodistribution of chemically modified bacteriophage MS2. Mol Pharm. 2013 Jan 7; 10(1):69-76. PMID: 23214968.
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      17. Dang LC, O'Neil J, Jagust WJ. Genetic effects on behavior are mediated by neurotransmitters and large-scale neural networks. Neuroimage. 2013 Feb 1; 66:203-14. PMID: 23142068.
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      18. Vandehey NT, O'Neil J, Slowey AJ, Boutchko R, Druhan JL, Moses WW, Nico PS. Monitoring Tc dynamics in a bioreduced sediment: an investigation with gamma camera imaging of (99m)Tc-pertechnetate and (99m)Tc-DTPA. Environ Sci Technol. 2012 Nov 20; 46(22):12583-90. PMID: 23078357.
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      19. Dang LC, O'Neil J, Jagust WJ. Dopamine supports coupling of attention-related networks. J Neurosci. 2012 Jul 11; 32(28):9582-7. PMID: 22787044.
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      20. Dang LC, Donde A, Madison C, O'Neil J, Jagust WJ. Striatal dopamine influences the default mode network to affect shifting between object features. J Cogn Neurosci. 2012 Sep; 24(9):1960-70. PMID: 22640392.
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      21. Landau SM, Marks SM, Mormino EC, Rabinovici GD, Oh H, O'Neil J, Wilson RS, Jagust WJ. Association of lifetime cognitive engagement and low ß-amyloid deposition. Arch Neurol. 2012 May; 69(5):623-29. PMID: 22271235.
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      22. Mitchell JM, O'Neil J, Janabi M, Marks SM, Jagust WJ, Fields HL. Alcohol consumption induces endogenous opioid release in the human orbitofrontal cortex and nucleus accumbens. Sci Transl Med. 2012 Jan 11; 4(116):116ra6. PMID: 22238334.
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      23. Boutchko R, Rayz VL, Vandehey NT, O'Neil J, Budinger TF, Nico PS, Druhan JL, Saloner DA, Gullberg GT, Moses WW. Imaging and modeling of flow in porous media using clinical nuclear emission tomography systems and computational fluid dynamics. J Appl Geophy. 2012 Jan; 76:74-81. PMID: 24917693.
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      24. Rabinovici GD, Rosen HJ, Alkalay A, Kornak J, Furst AJ, Agarwal N, Mormino EC, O'Neil J, Janabi M, Karydas A, Growdon ME, Jang JY, Huang EJ, Dearmond SJ, Trojanowski JQ, Grinberg LT, Gorno-Tempini ML, Seeley WW, Miller BL, Jagust WJ. Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD. Neurology. 2011 Dec 6; 77(23):2034-42. PMID: 22131541.
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      25. Rosenbloom MH, Alkalay A, Agarwal N, Baker SL, O'Neil J, Janabi M, Yen IV, Growdon M, Jang J, Madison C, Mormino EC, Rosen HJ, Gorno-Tempini ML, Weiner MW, Miller BL, Jagust WJ, Rabinovici GD. Distinct clinical and metabolic deficits in PCA and AD are not related to amyloid distribution. Neurology. 2011 May 24; 76(21):1789-96. PMID: 21525424.
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      26. Klostermann EC, Braskie MN, Landau SM, O'Neil J, Jagust WJ. Dopamine and frontostriatal networks in cognitive aging. Neurobiol Aging. 2012 Mar; 33(3):623.e15-24. PMID: 21511369.
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      27. Vasdev N, Dorff PN, O'Neil J, Chin FT, Hanrahan S, VanBrocklin HF. Metabolic stability of 6,7-dialkoxy-4-(2-, 3- and 4-[18F]fluoroanilino)quinazolines, potential EGFR imaging probes. Bioorg Med Chem. 2011 May 1; 19(9):2959-65. PMID: 21478021.
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      28. Braskie MN, Landau SM, Wilcox CE, Taylor SD, O'Neil J, Baker SL, Madison CM, Jagust WJ. Correlations of striatal dopamine synthesis with default network deactivations during working memory in younger adults. Hum Brain Mapp. 2011 Jun; 32(6):947-61. PMID: 20578173.
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      29. Rabinovici GD, Furst AJ, Alkalay A, Racine CA, O'Neil J, Janabi M, Baker SL, Agarwal N, Bonasera SJ, Mormino EC, Weiner MW, Gorno-Tempini ML, Rosen HJ, Miller BL, Jagust WJ. Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden. Brain. 2010 Feb; 133(Pt 2):512-28. PMID: 20080878.
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      30. Braskie MN, Wilcox CE, Landau SM, O'Neil J, Baker SL, Madison CM, Kluth JT, Jagust WJ. Relationship of striatal dopamine synthesis capacity to age and cognition. J Neurosci. 2008 Dec 24; 28(52):14320-8. PMID: 19109513.
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      31. Rabinovici GD, Jagust WJ, Furst AJ, Ogar JM, Racine CA, Mormino EC, O'Neil J, Lal RA, Dronkers NF, Miller BL, Gorno-Tempini ML. Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia. Ann Neurol. 2008 Oct; 64(4):388-401. PMID: 18991338.
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      32. Landau SM, Lal R, O'Neil J, Baker S, Jagust WJ. Striatal dopamine and working memory. Cereb Cortex. 2009 Feb; 19(2):445-54. PMID: 18550595.
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      33. Hooker JM, O'Neil J, Romanini DW, Taylor SE, Francis MB. Genome-free viral capsids as carriers for positron emission tomography radiolabels. Mol Imaging Biol. 2008 Jul-Aug; 10(4):182-91. PMID: 18437498.
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      34. Eberling JL, Bankiewicz KS, O'Neil J, Jagust WJ. PET 6-[F]fluoro-L-m-tyrosine Studies of Dopaminergic Function in Human and Nonhuman Primates. Front Hum Neurosci. 2007; 1:9. PMID: 18958223.
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      35. Boxer AL, Rabinovici GD, Kepe V, Goldman J, Furst AJ, Huang SC, Baker SL, O'neil JP, Chui H, Geschwind MD, Small GW, Barrio JR, Jagust W, Miller BL. Amyloid imaging in distinguishing atypical prion disease from Alzheimer disease. Neurology. 2007 Jul 17; 69(3):283-90. PMID: 17636066.
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      36. Rabinovici GD, Furst AJ, O'Neil J, Racine CA, Mormino EC, Baker SL, Chetty S, Patel P, Pagliaro TA, Klunk WE, Mathis CA, Rosen HJ, Miller BL, Jagust WJ. 11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration. Neurology. 2007 Apr 10; 68(15):1205-12. PMID: 17420404.
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      37. VanBrocklin HF, Hanrahan SM, Enas JD, Nandanan E, O'Neil J. Mitochondrial avid radioprobes. Preparation and evaluation of 7'(Z)-[125I]iodorotenone and 7'(Z)-[125I]iodorotenol. Nucl Med Biol. 2007 Jan; 34(1):109-16. PMID: 17210467.
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      38. Powell J, O'Neil J. Production of [15O]water at low-energy proton cyclotrons. Appl Radiat Isot. 2006 Jul; 64(7):755-9. PMID: 16617023.
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      39. VanBrocklin HF, Blagoev M, Hoepping A, O'Neil J, Klose M, Schubiger PA, Ametamey S. A new precursor for the preparation of 6-[18F]Fluoro-L-m-tyrosine ([18F]FMT): efficient synthesis and comparison of radiolabeling. Appl Radiat Isot. 2004 Dec; 61(6):1289-94. PMID: 15388123.
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      40. Marshall RC, Powers-Risius P, Reutter BW, O'Neil J, La Belle M, Huesman RH, VanBrocklin HF. Kinetic analysis of 18F-fluorodihydrorotenone as a deposited myocardial flow tracer: comparison to 201Tl. J Nucl Med. 2004 Nov; 45(11):1950-9. PMID: 15534068.
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      41. Eberling JL, Roberts JA, Taylor SE, VanBrocklin HF, O'Neil J, Nordahl TE. No effect of age and estrogen on aromatic L- amino acid decarboxylase activity in rhesus monkey brain. Neurobiol Aging. 2002 May-Jun; 23(3):479-83. PMID: 11959410.
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      42. Jordan S, Bankiewicz KS, Eberling JL, VanBrocklin HF, O'Neil J, Jagust WJ. An in vivo microdialysis study of striatal 6-[18F]fluoro-L-m-tyrosine metabolism. Neurochem Res. 1998 Apr; 23(4):513-7. PMID: 9566585.
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      43. Jordan S, Eberling JL, Bankiewicz KS, Rosenberg D, Coxson PG, VanBrocklin HF, O'Neil J, Emborg ME, Jagust WJ. 6-[18F]fluoro-L-m-tyrosine: metabolism, positron emission tomography kinetics, and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine lesions in primates. Brain Res. 1997 Mar 7; 750(1-2):264-76. PMID: 9098552.
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      44. Bonasera TA, O'Neil J, Xu M, Dobkin JA, Cutler PD, Lich LL, Choe YS, Katzenellenbogen JA, Welch MJ. Preclinical evaluation of fluorine-18-labeled androgen receptor ligands in baboons. J Nucl Med. 1996 Jun; 37(6):1009-15. PMID: 8683293.
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      45. VanBrocklin HF, Liu A, Welch MJ, O'Neil J, Katzenellenbogen JA. The synthesis of 7 alpha-methyl-substituted estrogens labeled with fluorine-18: potential breast tumor imaging agents. Steroids. 1994 Jan; 59(1):34-45. PMID: 8140600.
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      46. Kochanny MJ, VanBrocklin HF, Kym PR, Carlson KE, O'Neil J, Bonasera TA, Welch MJ, Katzenellenbogen JA. Fluorine-18-labeled progestin ketals: synthesis and target tissue uptake selectivity of potential imaging agents for receptor-positive breast tumors. J Med Chem. 1993 Apr 30; 36(9):1120-7. PMID: 8487253.
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