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    Singer, Brett

    Title
    SchoolLawrence Berkeley National Lab
    DepartmentEnergy Analysis Env Impacts
    Address1 Cyclotron Road
    Berkeley CA 94720
    Phone510/486-4779
    vCardDownload vCard

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Singer B, Delp WW, Black DR, Walker IS. Measured performance of filtration and ventilation systems for fine and ultrafine particles and ozone in an unoccupied modern California house. Indoor Air. 2016 Dec 05. PMID: 27917545.
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      2. Mullen NA, Li J, Russell ML, Spears M, Less BD, Singer B. Results of the California Healthy Homes Indoor Air Quality Study of 2011-2013: impact of natural gas appliances on air pollutant concentrations. Indoor Air. 2016 Apr; 26(2):231-45. PMID: 25647016.
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      3. Hult EL, Willem H, Price PN, Hotchi T, Russell ML, Singer B. Formaldehyde and acetaldehyde exposure mitigation in US residences: in-home measurements of ventilation control and source control. Indoor Air. 2015 Oct; 25(5):523-35. PMID: 25252109.
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      4. Lunden MM, Delp WW, Singer B. Capture efficiency of cooking-related fine and ultrafine particles by residential exhaust hoods. Indoor Air. 2015 Feb; 25(1):45-58. PMID: 24750219.
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      5. Logue JM, Klepeis NE, Lobscheid AB, Singer B. Pollutant exposures from natural gas cooking burners: a simulation-based assessment for southern california. Environ Health Perspect. 2014 Jan; 122(1):43-50. PMID: 24192135.
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      6. Delp WW, Singer B. Performance assessment of U.S. residential cooking exhaust hoods. Environ Sci Technol. 2012 Jun 5; 46(11):6167-73. PMID: 22568807.
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      7. Singer B, Delp WW, Price PN, Apte MG. Performance of installed cooking exhaust devices. Indoor Air. 2012 Jun; 22(3):224-34. PMID: 22044446.
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      8. Logue JM, Price PN, Sherman MH, Singer B. A method to estimate the chronic health impact of air pollutants in U.S. residences. Environ Health Perspect. 2012 Feb; 120(2):216-22. PMID: 22094717.
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      9. Matt GE, Quintana PJ, Destaillats H, Gundel LA, Sleiman M, Singer B, Jacob P, Benowitz N, Winickoff JP, Rehan V, Talbot P, Schick S, Samet J, Wang Y, Hang B, Martins-Green M, Pankow JF, Hovell MF. Thirdhand tobacco smoke: emerging evidence and arguments for a multidisciplinary research agenda. Environ Health Perspect. 2011 Sep; 119(9):1218-26. PMID: 21628107.
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      10. Logue JM, McKone TE, Sherman MH, Singer B. Hazard assessment of chemical air contaminants measured in residences. Indoor Air. 2011 Apr; 21(2):92-109. PMID: 21392118.
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      11. Sleiman M, Gundel LA, Pankow JF, Jacob P, Singer B, Destaillats H. Formation of carcinogens indoors by surface-mediated reactions of nicotine with nitrous acid, leading to potential thirdhand smoke hazards. Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15):6576-81. PMID: 20142504.
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      12. Bhangar S, Cowlin SC, Singer B, Sextro RG, Nazaroff WW. Ozone levels in passenger cabins of commercial aircraft on North American and transoceanic routes. Environ Sci Technol. 2008 Jun 1; 42(11):3938-43. PMID: 18589948.
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      13. Destaillats H, Lunden MM, Singer B, Coleman BK, Hodgson AT, Weschler CJ, Nazaroff WW. Indoor secondary pollutants from household product emissions in the presence of ozone: A bench-scale chamber study. Environ Sci Technol. 2006 Jul 15; 40(14):4421-8. PMID: 16903280.
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      14. Singer B, Destaillats H, Hodgson AT, Nazaroff WW. Cleaning products and air fresheners: emissions and resulting concentrations of glycol ethers and terpenoids. Indoor Air. 2006 Jun; 16(3):179-91. PMID: 16683937.
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      15. Destaillats H, Singer B, Lee SK, Gundel LA. Effect of ozone on nicotine desorption from model surfaces: evidence for heterogeneous chemistry. Environ Sci Technol. 2006 Mar 15; 40(6):1799-805. PMID: 16570600.
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      16. Singer B, Hodgson AT, Destaillats H, Hotchi T, Revzan KL, Sextro RG. Indoor sorption of surrogates for sarin and related nerve agents. Environ Sci Technol. 2005 May 1; 39(9):3203-14. PMID: 15926571.
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      17. Guliaev AB, Singer B, Hang B. Chloroethylnitrosourea-derived ethano cytosine and adenine adducts are substrates for Escherichia coli glycosylases excising analogous etheno adducts. DNA Repair (Amst). 2004 Oct 5; 3(10):1311-21. PMID: 15336626.
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      18. Kim JJ, Smorodinsky S, Lipsett M, Singer B, Hodgson AT, Ostro B. Traffic-related air pollution near busy roads: the East Bay Children's Respiratory Health Study. Am J Respir Crit Care Med. 2004 Sep 1; 170(5):520-6. PMID: 15184208.
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      19. Guliaev AB, Hang B, Singer B. Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C. Nucleic Acids Res. 2004; 32(9):2844-52. PMID: 15155853.
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      20. Nazaroff WW, Singer B. Inhalation of hazardous air pollutants from environmental tobacco smoke in US residences. J Expo Anal Environ Epidemiol. 2004; 14 Suppl 1:S71-7. PMID: 15118748.
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      21. Hang B, Chenna A, Guliaev AB, Singer B. Miscoding properties of 1,N6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1,3-bis(2-chloroethyl)-1-nitrosourea. Mutat Res. 2003 Oct 29; 531(1-2):191-203. PMID: 14637255.
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      22. Hang B, Singer B. Protein-protein interactions involving DNA glycosylases. Chem Res Toxicol. 2003 Oct; 16(10):1181-95. PMID: 14565759.
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      23. Singer B, Wenzel TP. Estimated emission reductions from California's enhanced Smog Check program. Environ Sci Technol. 2003 Jun 1; 37(11):2588-95. PMID: 12831048.
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      24. Guliaev AB, Hang B, Singer B. Structural insights by molecular dynamics simulations into differential repair efficiency for ethano-A versus etheno-A adducts by the human alkylpurine-DNA N-glycosylase. Nucleic Acids Res. 2002 Sep 1; 30(17):3778-87. PMID: 12202763.
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      25. Singer B, Hodgson AT, Guevarra KS, Hawley EL, Nazaroff WW. Gas-phase organics in environmental tobacco smoke. 1. Effects of smoking rate, ventilation, and furnishing level on emission factors. Environ Sci Technol. 2002 Mar 1; 36(5):846-53. PMID: 11918006.
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      26. Hang B, Downing G, Guliaev AB, Singer B. Novel activity of Escherichia coli mismatch uracil-DNA glycosylase (Mug) excising 8-(hydroxymethyl)-3,N4-ethenocytosine, a potential product resulting from glycidaldehyde reaction. Biochemistry. 2002 Feb 19; 41(7):2158-65. PMID: 11841206.
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      27. Singer B, Medina M, Zhang Y, Wang Z, Guliaev AB, Hang B. 8-(Hydroxymethyl)-3,N(4)-etheno-C, a potential carcinogenic glycidaldehyde product, miscodes in vitro using mammalian DNA polymerases. Biochemistry. 2002 Feb 12; 41(6):1778-85. PMID: 11827522.
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      28. Sági J, Guliaev AB, Singer B. 15-mer DNA duplexes containing an abasic site are thermodynamically more stable with adjacent purines than with pyrimidines. Biochemistry. 2001 Apr 3; 40(13):3859-68. PMID: 11300765.
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      29. Guliaev AB, Sági J, Singer B. Sequence-dependent conformational perturbation in DNA duplexes containing an epsilonA.T mismatch using molecular dynamics simulation. Carcinogenesis. 2000 Sep; 21(9):1727-36. PMID: 10964105.
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      30. Sági J, Perry A, Hang B, Singer B. Differential destabilization of the DNA oligonucleotide double helix by a T.G mismatch, 3,N(4)-ethenocytosine, 3,N(4)-ethanocytosine, or an 8-(hydroxymethyl)-3,N(4)-ethenocytosine adduct incorporated into the same sequence contexts. Chem Res Toxicol. 2000 Sep; 13(9):839-45. PMID: 10995256.
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      31. Singer B, Hang B. Nucleic acid sequence and repair: role of adduct, neighbor bases and enzyme specificity. Carcinogenesis. 2000 Jun; 21(6):1071-8. PMID: 10836993.
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      32. Chenna A, Perry A, Singer B. Synthesis of 8-(hydroxymethyl)-3,N(4)-etheno-2'-deoxycytidine, a potential carcinogenic glycidaldehyde adduct, and its site-specific incorporation into DNA oligonucleotides. Chem Res Toxicol. 2000 Mar; 13(3):208-13. PMID: 10725118.
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      33. Singer B, Kirchstetter TW, Harley RA, Kendall GR, Hesson JM. A Fuel-Based Approach to Estimating Motor Vehicle Cold-Start Emissions. J Air Waste Manag Assoc. 1999 Feb; 49(2):125-135. PMID: 28085655.
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      34. Singer B, Hang B. Mammalian enzymatic repair of etheno and para-benzoquinone exocyclic adducts derived from the carcinogens vinyl chloride and benzene. IARC Sci Publ. 1999; (150):233-47. PMID: 10626224.
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      35. Chenna A, Maruenda H, Singer B. Synthesis of para-benzoquinone and 1,3-bis(2-chloroethyl)nitrosourea adducts and their incorporation into oligonucleotides. IARC Sci Publ. 1999; (150):89-101. PMID: 10626211.
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      36. Sági J, Singer B. Thermal destabilization of DNA oligonucleotide duplexes by exocyclic adducts on adenine or cytosine depends on both the base and the size of adduct. IARC Sci Publ. 1999; (150):191-6. PMID: 10626220.
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      37. Hang B, Sági J, Singer B. Correlation between sequence-dependent glycosylase repair and the thermal stability of oligonucleotide duplexes containing 1, N6-ethenoadenine. J Biol Chem. 1998 Dec 11; 273(50):33406-13. PMID: 9837917.
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      38. Hang B, Medina M, Fraenkel-Conrat H, Singer B. A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch. Proc Natl Acad Sci U S A. 1998 Nov 10; 95(23):13561-6. PMID: 9811839.
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      39. Hang B, Chenna A, Sági J, Singer B. Differential cleavage of oligonucleotides containing the benzene-derived adduct, 1,N6-benzetheno-dA, by the major human AP endonuclease HAP1 and Escherichia coli exonuclease III and endonuclease IV. Carcinogenesis. 1998 Aug; 19(8):1339-43. PMID: 9744526.
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      40. Sági J, Chenna A, Hang B, Singer B. A single cyclic p-benzoquinone adduct can destabilize a DNA oligonucleotide duplex. Chem Res Toxicol. 1998 Apr; 11(4):329-34. PMID: 9548803.
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      41. Hang B, Rothwell DG, Sagi J, Hickson ID, Singer B. Evidence for a common active site for cleavage of an AP site and the benzene-derived exocyclic adduct, 3,N4-benzetheno-dC, in the major human AP endonuclease. Biochemistry. 1997 Dec 9; 36(49):15411-8. PMID: 9398271.
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      42. Hang B, Singer B, Margison GP, Elder RH. Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine. Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):12869-74. PMID: 9371767.
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      43. Litinski V, Chenna A, Sagi J, Singer B. Sequence context is an important determinant in the mutagenic potential of 1,N6-ethenodeoxyadenosine (epsilonA): formation of epsilonA basepairs and elongation in defined templates. Carcinogenesis. 1997 Aug; 18(8):1609-15. PMID: 9276637.
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      44. Singer B, Hang B. What structural features determine repair enzyme specificity and mechanism in chemically modified DNA? Chem Res Toxicol. 1997 Jul; 10(7):713-32. PMID: 9250405.
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      45. Hang B, Chenna A, Fraenkel-Conrat H, Singer B. An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5' cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP site. Proc Natl Acad Sci U S A. 1996 Nov 26; 93(24):13737-41. PMID: 8943004.
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      46. Rao S, Chenna A, Slupska M, Singer B. Replication of O4-methylthymine-containing oligonucleotides: effect of 3' and 5' flanking bases on formation and extension of O4-methylthymine . guanine basepairs. Mutat Res. 1996 Sep 23; 356(2):179-85. PMID: 8841483.
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      47. Singer B, Harley RA. A Fuel-Based Motor Vehicle Emission Inventory. J Air Waste Manag Assoc. 1996 Jun; 46(6):581-593. PMID: 28065126.
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      48. Hang B, Chenna A, Rao S, Singer B. 1,N6-ethenoadenine and 3,N4-ethenocytosine are excised by separate human DNA glycosylases. Carcinogenesis. 1996 Jan; 17(1):155-7. PMID: 8565126.
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      49. Chenna A, Singer B. Large scale synthesis of p-benzoquinone-2'-deoxycytidine and p-benzoquinone-2'-deoxyadenosine adducts and their site-specific incorporation into DNA oligonucleotides. Chem Res Toxicol. 1995 Sep; 8(6):865-74. PMID: 7492736.
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      50. Chenna A, Hang B, Rydberg B, Kim E, Pongracz K, Bodell WJ, Singer B. The benzene metabolite p-benzoquinone forms adducts with DNA bases that are excised by a repair activity from human cells that differs from an ethenoadenine glycosylase. Proc Natl Acad Sci U S A. 1995 Jun 20; 92(13):5890-4. PMID: 7597048.
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      51. Menichini P, Mroczkowska MM, Singer B. Enzyme-dependent pausing during in vitro replication of O4-methylthymine in a defined oligonucleotide sequence. Mutat Res. 1994 May 1; 307(1):53-9. PMID: 7513824.
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      52. Dosanjh MK, Roy R, Mitra S, Singer B. 1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase). Biochemistry. 1994 Feb 22; 33(7):1624-8. PMID: 8110764.
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      53. Dosanjh MK, Chenna A, Kim E, Fraenkel-Conrat H, Samson L, Singer B. All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase. Proc Natl Acad Sci U S A. 1994 Feb 1; 91(3):1024-8. PMID: 8302827.
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      54. Dosanjh MK, Loechler EL, Singer B. Evidence from in vitro replication that O6-methylguanine can adopt multiple conformations. Proc Natl Acad Sci U S A. 1993 May 1; 90(9):3983-7. PMID: 8483914.
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      55. Singer B, Antoccia A, Basu AK, Dosanjh MK, Fraenkel-Conrat H, Gallagher PE, Kusmierek JT, Qiu ZH, Rydberg B. Both purified human 1,N6-ethenoadenine-binding protein and purified human 3-methyladenine-DNA glycosylase act on 1,N6-ethenoadenine and 3-methyladenine. Proc Natl Acad Sci U S A. 1992 Oct 15; 89(20):9386-90. PMID: 1409645.
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      56. Rydberg B, Qiu ZH, Dosanjh MK, Singer B. Partial purification of a human DNA glycosylase acting on the cyclic carcinogen adduct 1,N6-ethenodeoxyadenosine. Cancer Res. 1992 Mar 1; 52(5):1377-9. PMID: 1737401.
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      57. Rydberg B, Dosanjh MK, Singer B. Human cells contain protein specifically binding to a single 1,N6-ethenoadenine in a DNA fragment. Proc Natl Acad Sci U S A. 1991 Aug 1; 88(15):6839-42. PMID: 1862108.
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      58. Singer B, Essigmann JM. Site-specific mutagenesis: retrospective and prospective. Carcinogenesis. 1991 Jun; 12(6):949-55. PMID: 2044201.
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      59. Singer B, Kusmierek JT, Folkman W, Chavez F, Dosanjh MK. Evidence for the mutagenic potential of the vinyl chloride induced adduct, N2, 3-etheno-deoxyguanosine, using a site-directed kinetic assay. Carcinogenesis. 1991 Apr; 12(4):745-7. PMID: 2013138.
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      60. Singer B, Dosanjh MK. Site-directed mutagenesis for quantitation of base-base interactions at defined sites. Mutat Res. 1990 Nov-Dec; 233(1-2):45-51. PMID: 2233812.
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      61. Folkman W, Kusmierek JT, Singer B. A new one-step method for the preparation of 3',5'-bisphosphates of acid-labile deoxynucleosides. Chem Res Toxicol. 1990 Nov-Dec; 3(6):536-9. PMID: 2103324.
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      62. Dosanjh MK, Essigmann JM, Goodman MF, Singer B. Comparative efficiency of forming m4T.G versus m4T.A base pairs at a unique site by use of Escherichia coli DNA polymerase I (Klenow fragment) and Drosophila melanogaster polymerase alpha-primase complex. Biochemistry. 1990 May 15; 29(19):4698-703. PMID: 2115381.
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      63. Singer B, Chavez F, Goodman MF, Essigmann JM, Dosanjh MK. Effect of 3' flanking neighbors on kinetics of pairing of dCTP or dTTP opposite O6-methylguanine in a defined primed oligonucleotide when Escherichia coli DNA polymerase I is used. Proc Natl Acad Sci U S A. 1989 Nov; 86(21):8271-4. PMID: 2682644.
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      64. Singer B, Chavez F, Spengler SJ, Kusmierek JT, Mendelman L, Goodman MF. Comparison of polymerase insertion and extension kinetics of a series of O2-alkyldeoxythymidine triphosphates and O4-methyldeoxythymidine triphosphate. Biochemistry. 1989 Feb 21; 28(4):1478-83. PMID: 2719911.
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      65. Spengler SJ, Singer B. Formation of interstrand cross-links in chloroacetaldehyde-treated DNA demonstrated by ethidium bromide fluorescence. Cancer Res. 1988 Sep 1; 48(17):4804-6. PMID: 3409221.
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      66. Fraenkel-Conrat H, Singer B. Nucleoside adducts are formed by cooperative reaction of acetaldehyde and alcohols: possible mechanism for the role of ethanol in carcinogenesis. Proc Natl Acad Sci U S A. 1988 Jun; 85(11):3758-61. PMID: 3375239.
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